Penile Injections for Growth Featured PhotoPenile injections for growth have become increasingly popular among men seeking enhancement and rejuvenation. PRP Penile Injections are a form of Platelet Rich Plasma (PRP) therapy that can increase penile girth, treat erectile dysfunction, and enhance overall sexual performance. The procedure works by drawing a small amount of blood to isolate the platelets, then injecting the concentrated platelets into the penile tissue to stimulate growth factors.

As board certified urologists, our team at Comprehensive Urology are helping our male patients achieve firmer erections with more girth. It all begins by scheduling an appointment with us. 

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Kia Michel, MD

Kia Michel, MD

Written by Dr. Kia Michel, a board certified urologist, surgeon, and founding member of Comprehensive Urology in Beverly Hills, Los Angeles. Dr. Michel's expertise includes focal therapy (HIFU/TULSA), prostate cancer treatment, robotic surgery, and male enhancement treatments such as Shockwave Therapy for ED and penile injections.

Dr. Michel's Bio

Key Takeaways

  • Penile injections, including PRP therapy, aim to increase girth and improve erectile function
  • Results vary based on the individual patient’s medical history
  • Receiving treatment from a board certified urologist is crucial before considering penile injections for growth

Penis Rejuvenation Therapy

Penis rejuvenation therapy has emerged as a promising treatment option for those looking to improve erectile function and penile aesthetics. One popular method involves the use of platelet-rich plasma (PRP), which is believed to harness the body’s natural healing and regenerative properties.

PRP therapy involves extracting a small amount of the patient’s blood, separating the platelets and growth factors, and then reinjecting them into the penile tissue. This process is quick and nearly painless, with the entire procedure taking under an hour in most cases. Additionally, there is minimal downtime required, allowing patients to resume their normal activities shortly after treatment.

It’s important to note that results may vary, and this therapy is not a guaranteed solution for every individual. However, many patients have reported improvements in the following areas:

  • Erectile function: Increased blood flow and natural growth factors may contribute to improved erections and overall sexual function.
  • Penile size: Some individuals have experienced modest increases in both length and girth following PRP therapy.
  • Sensitivity: By stimulating the growth of new blood vessels and nerve endings, PRP can potentially enhance penile sensitivity for a more satisfying sexual experience.

In addition to PRP, there are other penile rejuvenation therapies available, such as the P-Shot and J-Shot. As with any medical treatment, it’s crucial to consult with a qualified professional to determine the best course of action for your specific needs and circumstances.

When considering penis rejuvenation therapy, it’s essential to weigh the benefits against potential risks and side effects. As this is a relatively new field, more research and clinical trials may be needed to fully understand the long-term implications and efficacy of these treatments. We also offer ThermiVa Vaginal Rejuvenation therapy for our female patients.

Understanding Penile Injections

Penile injections are a method used for treating erectile dysfunction, as well as for other purposes such as penile growth. The procedure involves injecting medication or other substances like platelet-rich plasma (PRP) into the penis to improve blood flow or to increase penile size.

There are several types of medications used in penile injections, particularly for treating erectile dysfunction. One example is the injection of alprostadil, which helps increase blood flow to the penis, leading to an erection in approximately 5 to 15 minutes.

Another type of penile injection is the P-Shot, which uses PRP to stimulate the growth of new cells in the penis. This procedure is typically combined with the use of a penis pump to ensure that the injected PRP works effectively.

When considering penile injections for growth, it’s important to note that there are limitations to the procedure. For example, fat injections involve taking fat from a fleshy part of the body and injecting it into the penis shaft. Although this can make the penis thicker, the results may be disappointing, with some of the injected fat spreading unevenly or being reabsorbed by the body. This could lead to a curved, unevenly shaped, and irregular looking penis.

As with any medical procedure, there are potential side effects and risks associated with penile injections. Some possible side effects include fainting, dizziness, and low blood pressure, while more serious complications like priapism (prolonged erections) and scarring can also occur if the injections are not done properly by trained professionals (UCSF Health).

Types of Penile Injections

There are several types of penile injections used for growth and enhancement. Some common options include hyaluronic acid fillers, biostimulatory fillers, fat injections, and platelet-rich plasma (PRP) injections.

Hyaluronic Acid Fillers

are a popular option for temporary penile growth. These fillers consist of a gel-like substance designed to add volume under the skin, often used in facial cosmetic procedures. Hhyaluronic acid fillers can be injected into the penis to increase girth temporarily. Results typically last between six months to a year, which is why patients normally schedule annual refreshers to maintain optimal results.

Biostimulatory Fillers

work similarly to hyaluronic acid fillers, but they encourage the growth of new collagen within the penis. These fillers provide volume, encourage natural tissue growth, and may have longer-lasting effects compared to hyaluronic acid fillers.

Fat Injections

involve taking fat from one part of the body, such as the stomach or thighs, and injecting it into the penis shaft. This technique is aimed at increasing the girth of the penis. However, the Mayo Clinic cautions that the results of fat injections can be disappointing, as the fat may spread unevenly or be reabsorbed by the body.

Platelet-Rich Plasma (PRP) Injections:

also known as the P-Shot, involves drawing blood from the patient, separating the platelets, and injecting the resulting plasma into the penis. According to Healthline, PRP injections can potentially improve erectile function, increase sensation, and enhance girth.

Botox Penile Injections:

Using the same Botox injections that help smooth out wrinkles in your skin and fill out your lips, Botox can be safely injected into the penis to increase blood flow, girth and erectile function.


Botox can also be injected into the scrotum to decrease wrinkles, reduce sweating, and decrease testicular pain.

It is important to consult with a medical professional before undergoing any penile injection procedure to ensure safety and appropriate expectations for results. While these injections may provide temporary growth and enhancement, they may not be suitable for everyone and may carry risks and side effects.

What is a P Shot?

A P-Shot (short for Priapus Shot) is a penile injection that uses platelet-rich plasma (PRP) derived from the patient’s blood. This injection is intended to aid in improving sexual performance, increasing penile size, and helping with erectile dysfunction.

What is Platelet-Rich Plasma (PRP) Therapy?

Platelet-Rich Plasma (PRP) therapy is a medical treatment that involves injecting a highly concentrated form of your own blood containing platelets into an injured or damaged area of your body, with the goal of promoting natural healing and reducing pain and inflammation. Platelets are essential components of blood that play a crucial role in blood clotting and tissue repair, as they release growth factors responsible for stimulating the healing process.

One potential application for PRP therapy is in treating male pattern baldness, where it has been shown to be effective in both preventing hair loss and promoting new hair growth source. PRP injections can also be used to stimulate hair growth after hair transplant procedures.

In the context of penile injections for growth, the PRP procedure is referred to as the P-Shot. The treatment involves taking PRP from your blood and injecting it directly into the penis, with the intention of repairing damaged tissues and improving erectile function source. Some reports suggest that the P-shot can lead to stronger erections, increased sensation, better performance, and even augment penile length and girth by improving blood flow to the penis source.

How Penile Injections Work

Penile injections, also known as intracavernosal injections, are a treatment option for men experiencing erectile dysfunction (ED) or seeking penis enlargement. This section will provide an overview of how penile injections work, focusing on the Preparation and Injection Process.


Before administering a penile injection, it’s essential for the individual and healthcare provider to discuss the suitability of this treatment option. In some cases, patients may need to undergo tests and assessments to determine the appropriate medication and dosage for their needs.

When it’s time to prepare for the injection, the patient should gather the required materials, including a medication vial, sterile syringe, alcohol wipes, and a sharps container for used syringes1. The injection site on the penis should be cleaned with an alcohol wipe to minimize the risk of infection.

Penile injection Process

The Physician Assistant or Nurse will draw the patient’s blood and use a centrifuge to separate the platelet-rich plasma (PRP). They then load the prepared medication or PRP into the sterile syringe. The patient or healthcare provider will carefully inject the medication into the penis, usually into the corpora cavernosa, which consists of two sponge-like tissue chambers responsible for erections.

Once the injection is complete, the patient should apply pressure to the injection site for a few minutes to minimize bruising and discard the used syringe in the sharps container. The injected medication or PRP promotes increased blood flow to the penis, resulting in an erection or temporary growth.

Effectiveness and Growth Potential of PRP Penile Injections

Platelet-rich plasma (PRP) injections are a relatively new treatment option for penile concerns such as erectile dysfunction (ED) and Peyronie’s disease (PD). In Peyronie’s disease in particular, there is often a trauma to the penile tissue. Platelets do their best work when they are repairing damaged blood vessels and vascular tissue, so they have been found to be very effective when penile trauma has occurred. Erectile dysfunction that stems from some type of damage to the penis are likely to have the best results from PRP penile injections. This is because the platelets are rich in growth factors and are believed to promote tissue regeneration and improve blood flow to the penis. This improved blood flow may lead to a growth in penile size and better erectile function.

In comparison to traditional treatment options for ED and PD, PRP injections and stem cell therapy offer a less invasive and potentially more efficient approach. At Comprehensive Urology, we believe in combing therapies that can amplify each other so that our patients are achieving optimal results. We’re currently running a trial to study the effectiveness of Pulsed PRP, which is a combination of Pulse wave therapy (also called shockwave therapy for ED) with PRP Penile Injections. Since shockwave therapy stimulates nerve and blood vessel growth, the introduction of additional growth factors from PRP therapy could further enhance penile tissue growth. Schedule your appointment today to enroll in the trial. 

PRP Penile Injection Combined with Shockwave Therapy

PRP (Platelet-Rich Plasma) penile injections and Low-Intensity Shockwave Therapy (LiSWT) are emerging treatments for conditions such as erectile dysfunction and Peyronie’s disease. These regenerative therapies work by promoting new cellular growth and repairing damaged penile tissues.

In recent years, there has been growing interest in combining PRP injections with LiSWT to enhance treatment effectiveness. PRP is derived autologously from a patient’s plasma and is then injected into the penile tissue. LiSWT, on the other hand, involves the use of targeted low-intensity shockwaves to stimulate the repair process in penile tissues.

The idea behind combining these treatments is to leverage the benefits of both therapies, creating a synergistic effect. PRP provides growth factors and other essential proteins that aid in tissue regeneration, while LiSWT stimulates blood flow and encourages the formation of new blood vessels in the treated area.

A clinical trial investigating the effectiveness of combined PRP and Li-ESWT treatments showed promising results for improving erectile function. Participants in the trial received weekly Li-ESWT treatments for three weeks, followed by a PRP injection on the same day as the last shockwave treatment.

Although further research is needed to fully understand the potential benefits and optimal treatment protocols, the combined approach of PRP injections and LiSWT appears to hold promise for patients seeking innovative and minimally invasive treatments for penile health concerns.

Risks and Side Effects

Male sexual dysfunction may play a role in your ability to have a satisficing erection/ Be sure to consult a board certified urologist whenever considering any type of male enhancement as underlying causes of male sexual dysfunction need to been addressed in addition to penile injection therapy. Contact our team at Comprehensive Urology today.

Immediate Side Effects

Some immediate side effects of penile injections for growth can occur after the procedure. These may include bruising, bleeding, or swelling at the place of injection, as well as mild burning along the penis. In rarer cases, patients may experience more severe effects such as fainting, dizziness, blurred vision, and nausea. It’s essential for patients to be aware of these potential reactions and seek medical assistance if any severe symptoms occur.

Long-Term Risks

While complications associated with penile injections for growth tend to be mild and rare, there are some potential long-term risks to consider. One possible issue is the formation of cysts, bumps, lumps, or skin irregularities in the treated area. Another concern comes from the use of hyaluronic acid injections, which can cause postoperative complications that might affect patient satisfaction. It is crucial for individuals considering this procedure to discuss all possible risks and complications with their healthcare provider before undergoing treatment.

In conclusion, while penile injections for growth can offer potential benefits, it is essential to be aware of the immediate side effects and long-term risks involved. Consulting with a healthcare professional and carefully weighing the pros and cons are crucial steps in making an informed decision.

Alternatives to Penile Injections

There are several alternative methods for penile growth apart from penile injections. One such option is penile traction therapy. This method involves stretching the penis with a self-applied mechanical device for a period of time to improve penile length, curvature, and deformity. These devices may need to be worn for as little as 30 minutes to as much as three to eight hours a day to achieve benefits 1.

Another approach involves using “home” methods to enlarge the penis without medical supervision. Some common techniques include:

  • Penile tape, also used in foreskin restoration
  • Penile weight system
  • Penile stretching using a controlled stretch device2

However, these methods have not been scientifically proven to be effective, and their safety is questionable.

Erectile dysfunction (ED) medication, such as Viagra, is another alternative for those who suffer from ED in addition to seeking penile growth. These medications typically take 30 to 60 minutes to achieve an erection3. While ED medication can improve the quality and duration of erections, it does not directly contribute to penile growth.

In conclusion, it is crucial for individuals considering any of these alternatives to speak with a healthcare professional to ensure they are choosing the safest and most effective method for their specific situation.

PRP Penis Injection Clinical Studies Summary

Platelet-Rich Plasma (PRP) injections have emerged as a potential treatment option for men experiencing erectile dysfunction (ED). PRP is derived from a patient’s own plasma and is then injected into the penile tissue, with an aim to repair damaged tissue and promote cellular and vascular growth.

A double-blind, randomized, placebo controlled clinical trial assessing the efficacy and safety of PRP injections in patients with mild to moderate ED showed positive results. The study demonstrated that PRP injections improved key elements of the pathophysiological mechanisms leading to erectile dysfunction.

In addition to treating ED, some studies have evaluated the impact of PRP injections on men and couples with infertility. These studies report higher rates of erectile dysfunction in men diagnosed with male infertility compared to the general population.

Another study highlighting the potential of PRP injections revealed that erectile dysfunction is a common complication of cancer surgeries, such as radical prostatectomy for prostate cancer and radical cystectomy for bladder cancer. In these cases, Platelet Rich Plasma Therapy offers a promising solution to restore erectile function.

It is important to note that while the available clinical studies indicate potential benefits of using PRP injections to treat erectile dysfunction, further research is needed to establish PRP treatment as a standard treatment option. However, our patients are already seeing great results in our case studies. Come schedule a time to see us today.



How effective are penile growth injections?

Penile growth injections, such as P-Shots, can be effective in enhancing penile size and performance. The effectiveness depends on several factors, including individual response, health conditions, and the type of injection. Results may vary, and it’s important to consult with a qualified professional to determine if this treatment is suitable for you.

How long does a penile injection last?

The duration of the effects from penile injections can vary. Injections like the P-Shot can have effects lasting up to a year or more in some cases, while other treatments may need to be repeated more frequently. It’s essential to discuss expectations with your physician to ensure the best course of action for your needs.

Is the P Shot the Same thing as a Trimex Injection?

No, the P Shot and Trimex injection are not the same. While both treatments are penile injections aimed at improving sexual function, the P Shot uses platelet-rich plasma (PRP) to stimulate tissue growth, whereas Trimex injections typically contain a mix of three medications to achieve an erection.

Can P Shots be given to the Scrotum?

Normally, Botox injections are given to the scrotum in a procedure called scrotox to smooth out wrinkles and reduce sweating. PRP shots are still being studies for scrotal injections.

What is the success rate of P-Shot injections?

The success rate of P-Shot injections can vary, as individual results may depend on factors such as age, overall health, and lifestyle choices. Some patients report significant improvements, while others experience little to no change. It’s essential to consult with a professional to determine if the P-Shot is an appropriate option for you.

What is a Trimex Injection?

A Trimex injection is a mixture of three medications (papaverine, phentolamine, and alprostadil) that can help men achieve and maintain an erection. It is often used as a treatment option for erectile dysfunction, particularly when other methods have failed or are not suitable.

What are common side effects of penile injections?

Some common side effects of penile injections may include pain, infection, bruising, and scarring. In rare instances, penile injections can cause fainting, dizziness, or low blood pressure. If you experience any adverse effects or have concerns, it’s essential to contact your healthcare provider promptly.

Can PRP injections lead to penile enlargement?

PRP injections have shown potential in providing penile enlargement by utilizing the patient’s platelet-rich plasma containing growth factors. These growth factors are believed to stimulate tissue regeneration and rejuvenation. It is critical to consult with a board certified urologist to determine if PRP injections are a suitable treatment for your penile enlargement goals.

Where can I find male enlargement injections near me?

To find male enlargement injections near you, consider consulting with a board-certified plastic surgeon or a medical professional specializing in men’s sexual health. They will be able to discuss treatment options and help you decide on the best course of action based on your individual needs and goals. Make an appointment to see Dr. Kia Michel today and learn more about our Male Enhancement options and ThermiVa vaginal rejuvenation for women at Comprehensive Urology in Beverly Hills, Los Angeles.

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