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Summary

TRT Therapy (testosterone replacement therapy) help men with low testosterone to feel vibrant, to gain muscle mass, and to improve sexual performance. Urologist Kia Michel MD explains the options, benefits, and side effects of TRT Therapy.

man working out after starting TRT therapy at Comprehensive Urology in Los Angeles

TRT Therapy can be life changing for men who are experiencing declining testosterone levels. Typically starting around age 45, men naturally experience a decrease in testosterone. Low testosterone can be mistaken for depression, because men with low T lack energy, libido, and can be in a low mood. For the past 25 years, I’ve offered many middle aged and older men a fresh start on life with TRT Therapy. Let’s see if TRT is right for you.

Table of Contents

TRT Therapy Uses

Testosterone Replacement Therapy (TRT) is a treatment designed to address low testosterone levels. It is commonly used for conditions such as hypogonadism, impacting both men and women differently. It can also play a role in ensuring sufficient sperm count for those trying to get pregnant. Here, TRT involves specific applications and expected outcomes based on the individual’s needs.

TRT for Men

Men experiencing low testosterone may benefit significantly from TRT. This therapy helps in improving energy levels, increasing muscle mass, and enhancing sexual performance. Common forms of administration are injections, gels, patches, and pellets. Each form varies in terms of convenience and absorption rates.

In hypogonadism, where the body’s natural testosterone production is impaired, TRT can restore normal hormonal balance. Regular monitoring by healthcare professionals is essential to prevent adverse effects and adjust dosages.

TRT for Women

For women, TRT is less common but may be considered for those with exceptionally low testosterone levels. It can assist in improving energy, mood, and sexual drive. Dosage and form of administration typically differ from those used in men to avoid excessive hormonal shifts.

Women must be cautious due to potential masculinizing effects like body hair growth or voice changes. Monitoring is crucial to tailor the therapy to individual hormonal needs and avoid side effects. The therapy is often combined with other hormone treatments to achieve balanced results.

Before starting TRT, a thorough consultation with a healthcare provider is important to weigh benefits against risks and to choose the most appropriate method of delivery.

Testosterone Levels by Age Chart

Testosterone levels naturally vary throughout a person’s life. This hormone reaches its peak in late adolescence and gradually declines as a person ages. This chart can help you see if you have low testosterone for your age.

For adult men, a normal testosterone level is often considered to be between 300 and 1,000 ng/dL.

Testosterone Levels by Age Chart 

Age Group

Average Levels in Men (ng/dL)

0-5 months

75-400

1-5 years

<7-20

6-9 years

<7-20

10-11 years

<7-130

12-13 years

<7-800

14 years

<7-1,200

15-16 years

100-1,200

17-18 years

300-1,200

19+ years

265-923

Testosterone Levels Dropping Chart

Age Group

Testosterone Levels in Men (ng/dL)

Ages 18-19 and older

265-923

Ages 20-39

400-1080

Ages 40-59

350-890

Ages 60-70

196-859

Ages 70 and above

156-819

Women’s testosterone levels are substantially lower than men’s. Adult women typically have levels between 15 and 70 ng/dL. It is possible for a woman to have low testosterone in which TRT Therapy may be used in much smaller doses compared to men.

Remember, these charts show general ranges and each man may need more or less testosterone to feel energized, strong, and confident in their sexual function. Individual levels can vary based on several factors, including health status and lifestyle. Always consult with a board certified urologist for the most effective TRT program

TRT Therapy Results

Testosterone Replacement Therapy (TRT) can profoundly impact men’s physical and mental health. Key areas of interest include expected transformations before and after therapy, understanding contraindications, the importance of monitoring free testosterone levels, and achieving ideal testosterone levels during treatment.

Before and After TRT Therapy

Men undergoing TRT often report significant changes. Initially, many experience improved mental clarity within two weeks and heightened libido by eight weeks. Over the course of three to six months, increased muscle mass and reduced weight are common benefits. These transformations can greatly enhance quality of life. It’s important to set realistic expectations as the timeline and extent of results can vary based on factors such as age, health, and the chosen method of therapy administration.

TRT can be administered through injections, patches, gels, or pellets. Each method affects results differently, with injections often providing superior outcomes. Regular consultation with a healthcare provider is essential for assessing progress and making any necessary adjustments to the therapy.

Contraindications and Exclusions

While TRT offers various benefits, it is not suitable for everyone. People with past prostate or breast cancer or those with untreated sleep apnea should avoid TRT. It may also exacerbate conditions such as polycythemia, where there is an excess of red blood cells.

Before beginning therapy, a thorough medical evaluation is necessary. This evaluation includes assessing hormonal levels and understanding personal and family medical history. Any potential cardiovascular risks should be carefully evaluated, as testosterone therapy may increase the risk of certain heart conditions.

Checking Free Testosterone Levels

Monitoring free testosterone levels is crucial while on TRT. Free testosterone contributes significantly to the hormone’s physiological effects, as it is available to tissues. Regular blood tests can help determine the therapy’s effectiveness and whether adjustments are needed.

Free testosterone levels can be influenced by factors including age, sex hormone-binding globulin levels, and overall health. Ensuring levels are within the optimal range can maximize the benefits of TRT and minimize adverse effects. Physicians typically recommend maintaining regular testing intervals to ensure therapy is successful and safe.

Ideal Testosterone Levels on TRT

An ideal testosterone level for individuals on TRT can vary, but it generally falls within the mid to upper range of normal values. Normal levels are usually between 300-1000 ng/dL, but the specific goal should be personalized. Adjusting the treatment plan to align testosterone levels with these targets can improve physical health, mental clarity, and vitality.

Regular monitoring and consultation with healthcare providers help achieve and maintain these levels. Fluctuations outside the target range may require dosage adjustments or changes in the therapy delivery method. Working closely with medical professionals ensures the highest effectiveness of TRT.

TRT Delivery Methods

Testosterone Replacement Therapy (TRT) is available in several delivery methods, each with distinct advantages and considerations. The choice may depend on an individual’s lifestyle, preferences, and medical needs. Below is a detailed look at how these methods work.

TRT Intramuscular Injections

Intramuscular injections are among the most effective and commonly used TRT methods. They involve injecting testosterone directly into the muscle, typically every one to two weeks. This method allows for a controlled release of hormones and provides a stable level of testosterone in the bloodstream.

Benefits of intramuscular injections include consistent dosage and fewer application requirements compared to daily treatments. However, some individuals may experience discomfort at the injection site, and fluctuations in hormone levels can occur as the dose wears off over time. Despite these challenges, many find this method effective for achieving desired testosterone levels.

Testosterone Gel

Testosterone gel is applied topically, usually on the upper arms, shoulders, or abdomen. This method provides a steady release of testosterone through the skin. Its appeal lies in its ease of use and the ability to maintain consistent testosterone levels without the need for injections.

However, there are potential downsides, such as the risk of transferring the gel to others through skin contact. Users must also be cautious about application areas to avoid varying absorption rates. Despite these concerns, testosterone gel can be a convenient choice for those seeking a non-invasive TRT option.

Testosterone Patches

Transdermal testosterone patches deliver hormones through the skin. Typically applied once daily, these patches are placed on areas of the skin that are not frequently rubbed or exposed. They offer a consistent and steady release of testosterone, similar to the gel.

One challenge with patches is skin irritation, which some users may experience. Additionally, the adhesive may not always remain in place, reducing effectiveness. Nonetheless, for those seeking an easy and regular application, patches are a viable TRT method with proven effectiveness.

TRT Subcutaneous Pellets

Subcutaneous pellets involve inserting small pellets under the skin, usually in the area of the buttocks. These pellets steadily release testosterone over three to six months, minimizing the need for frequent applications or injections.

This method is advantageous for those seeking lower maintenance treatment. It reduces fluctuations in hormone levels and provides a long-lasting solution. However, the insertion process is a minor surgical procedure. Some patients may find the recovery process inconvenient, but the long-term benefits often outweigh this drawback.

TRT Oral Administration

Oral testosterone administration includes tablets or capsules that are taken daily. These are designed to be absorbed through the digestive system. Oral administration is straightforward and can easily be integrated into a daily routine.

However, oral testosterone is often considered less effective than other methods due to limited bioavailability. There is also potential stress on the liver over time. Though convenient, this method is typically less recommended, and individuals are advised to monitor liver health regularly if choosing this route.

TRT Testosterone Options

Testosterone Replacement Therapy (TRT) offers several administration options that can address low testosterone levels in different ways depending on individual preferences and medical advice. This section covers options such as testosterone cypionate, testosterone enanthate, testosterone boosters, Clomid for men, and TRT oral administration.

Testosterone Cypionate

Testosterone cypionate is a synthetic version of testosterone administered as an injectable solution. It is typically injected into the muscle, allowing gradual release into the bloodstream. This method provides sustained testosterone levels and is commonly prescribed for individuals with low testosterone. Testosterone cypionate is favored due to its long half-life, which means injections are required every 7 to 14 days. Patients appreciate the reduced frequency of injections compared to other options.

Testosterone Enanthate

Similar to testosterone cypionate, testosterone enanthate is another injectable form of testosterone. It is also injected intramuscularly and has a comparable release profile. Testosterone enanthate is often chosen for its availability and effectiveness. It requires dosing at intervals of 1 to 2 weeks, which helps maintain steady hormone levels. Both testosterone enanthate and cypionate are predominantly used for their efficacy in increasing testosterone levels over extended periods, minimizing the need for frequent administration.

Testosterone Booster

Testosterone boosters are dietary supplements designed to increase testosterone levels naturally. They often contain herbal extracts, vitamins, and minerals that support testosterone production. Common ingredients include fenugreek, zinc, and vitamin D. While testosterone boosters are less potent than prescription medications, they may be beneficial for individuals with slightly low testosterone or those looking to support overall health. These supplements may not be suitable for everyone and should be used under professional guidance to ensure safety and efficacy.

Clomid for Men

Clomid, generally used to treat female infertility, can also be prescribed for men with low testosterone. It functions as a selective estrogen receptor modulator (SERM), indirectly stimulating testosterone production by the testes. By blocking estrogen receptors in the brain, Clomid signals the pituitary gland to produce more luteinizing hormone, which in turn boosts testosterone levels. This option allows some men to preserve fertility while increasing testosterone, providing an alternative to standard TRT methods.

TRT Oral Administration

TRT oral administration includes testosterone pills or tablets, which are a less invasive option for increasing testosterone levels. Though convenient, oral testosterone is less commonly prescribed due to potential risks such as liver toxicity and less consistent hormone levels compared to injections or topical treatments. For some, oral administration may be an appealing option if injections are intolerable, but it requires careful monitoring by healthcare professionals to manage any associated risks effectively.

Benefits of TRT Therapy

Testosterone Replacement Therapy (TRT) offers a variety of benefits, including enhancements to physical health, psychological well-being, and sexual function. This hormone therapy can significantly impact overall vitality and well-being.

Physical Health Improvements

TRT can lead to improvements in muscle mass, bone density, and fat distribution. Individuals undergoing this therapy often experience an increase in muscle strength and a more defined physique. As testosterone levels increase, the metabolism may become more efficient, resulting in better energy utilization and potential weight management.

Bone health also benefits, as testosterone plays a critical role in maintaining bone density. This helps reduce the risk of fractures and osteoporosis, especially critical in aging men. People report feeling more energetic, improving day-to-day performance and quality of life. By promoting regular exercise alongside TRT, individuals may see heightened physical health benefits.

Psychological and Emotional Benefits

Testosterone affects psychological states like mood and cognitive function. TRT has been associated with decreased symptoms of depression and anxiety in individuals with low testosterone. As hormone levels rebalance, many report a boost in motivation and confidence.

Enhanced focus and mental clarity are also common. Individuals may find daily tasks easier to manage, contributing to an increased sense of productivity. With stabilized mood and improved outlook, TRT can significantly enhance one’s quality of life.

Sexual Function Enhancement

Enhancements in sexual health are often notable. Many patients experience an increased libido, which can be beneficial for those experiencing low libido. Improved erectile function is another key benefit.

TRT aids in the natural mechanisms of arousal and desire, potentially revitalizing intimate relationships. Though individual results can vary, the overall enhancement in sexual function can be substantial. Leveraging additional therapies like the STUD Protocol may offer compounded benefits for some individuals.

Fertility on TRT Therapy

While TRT can provide numerous benefits, it may affect fertility. Testosterone therapy can decrease sperm production, as external testosterone can suppress natural hormone feedback loops involved in sperm production. This may pose challenges for those looking to conceive.

Alternative treatments or additions such as hCG might be considered to preserve fertility while on TRT. It’s crucial for individuals to consult healthcare professionals about family planning when considering TRT. Understanding this aspect can help make informed decisions regarding treatment plans tailored to specific life goals and reproductive health.

Side Effects of TRT

Testosterone Replacement Therapy (TRT) can provide several benefits, but individuals must also be aware of potential side effects. Among these are changes in estradiol levels and the possible need for estrogen blockers, which require careful consideration and management.

Estradiol Levels

TRT can lead to an increase in estradiol levels in men. This occurs because testosterone can be converted into estrogen, specifically estradiol, through a process called aromatization. Elevated estradiol levels may induce side effects such as water retention, breast tenderness, or gynecomastia (enlarged breast tissue). Monitoring these levels every few months is crucial for managing and minimizing such effects. If Estradiol levels increase, estrogen blockers can be prescribed by your urologist.

Estradiol Levels Chart

Age Group

Estradiol Levels in Men (pg/mL)

Ages 20-39

37

Ages 40-59

33.9

Ages 60 and above

33.5

This chart will be used by urologists to determine if estradiol levels are increasing for men on TRT Therapy. Knowing your estradiol level can help the urologist adjust the testosterone dosages as well as determine whether you would benefit from estrogen blockers to maximize your testosterone levels while reducing side effects from estradiol. 

TRT and Estrogen Blockers

To combat increased estrogen levels, some individuals on TRT may be prescribed estrogen blockers or aromatase inhibitors. These medications work by reducing the conversion of testosterone to estrogen, thus helping to maintain hormone balance. Common blockers include anastrozole and letrozole, which can effectively manage estrogen-related side effects.

However, using estrogen blockers should be approached with caution. Overuse or incorrect dosing may lead to low estradiol levels, which can negatively impact bone health and mood. A healthcare provider can ensure the right balance by monitoring hormone levels and adjusting medication as needed. The goal is to achieve a therapeutic balance without compromising well-being.

Cost of TRT Therapy

Testosterone Replacement Therapy (TRT) costs can vary based on several factors, including location, type of treatment, and insurance coverage. Understanding these elements can help individuals make informed decisions about their financial commitment to TRT.

TRT Therapy Cost Considerations

The cost of TRT can range widely. Initial consultations usually range from $100 to $500, while diagnostic testing might add $500 to $1,000. Ongoing treatment costs, which include medications and follow-up appointments, typically add up to $1,200 to $3,000 annually. Some reports suggest monthly expenses for TRT might fall between $100 and $1,000 based on these variables.

Insurance can play a significant role in reducing these out-of-pocket costs. However, coverage depends on the insurance provider and the specifics of the policy. Therefore, it is crucial to check with the insurance company to determine what percentage, if any, they cover. Adjustments to therapy type or frequency may also affect the total cost, making personalized consultation important for financial planning. For more details, resources such as TRT Cost Breakdown provide comprehensive insights.

Online TRT Therapy

TRT Therapy can be done via a telehealth call if you do bloodwork at your local lab. An urologist can review your bloodwork and take your case history via secure video chat to prescribe a testosterone replacement therapy treatment program for you. You will need to follow up 2-3 months afterwards and have your testosterone levels checked to ensure you are on the correct dosage and TRT delivery method. Make an appointment to see one of our urologists today.

TRT Therapy Near Me

Finding TRT therapy locally often involves searching for a clinic that offers telehealth services. Many clinics provide online consultations, allowing patients to discuss symptoms and treatment plans from home. This approach not only saves time but also increases access to care for those living in remote areas. Local clinics may offer both virtual and in-person services to cater to diverse patient needs. These clinics can connect patients with medical professionals who specialize in hormone imbalances, making it easier to receive tailored treatments quickly and efficiently.

TRT Therapy at Comprehensive Urology in Los Angeles

Comprehensive Urology in Los Angeles has the best urologists in Los Angeles. They offer a mix of online and in-person services, ensuring flexibility and adaptability to patient needs. The clinic employs state-of-the-art techniques and equipment to conduct hormone evaluations and deliver effective treatment. Signing up for services involves an initial consultation to assess testosterone levels and discuss various therapy options. Follow-up appointments, whether online or in-person, are organized to monitor progress and adjust treatment plans accordingly. Their experienced medical staff is committed to offering detailed care to optimize patient health outcomes.

TRT Specialist Kia Michel MD

Dr. Kia Michel is a leading specialist in the field of TRT therapy. With a background in urology, Dr. Michel combines expertise with a comprehensive approach to hormone therapy. He offers services through both in-person visits and telehealth, making it accessible for a broad patient base. His practice focuses on thorough diagnostic evaluations to tailor treatment plans that address individual hormonal needs. Dr. Michel is known for his patient-centered approach, emphasizing clear communication and personalized care plans. Patients can expect detailed assessments and ongoing support throughout their treatment journey, making him a reputable choice for those seeking TRT therapy.

Stud - The Male Enhancement Guide for Peak Sexual Performance by Kia Michel MD book photo

STUD - The Male Enhancement Guide by Kia Michel, MD

Click the image to learn how to join the STUD Protocol at Comprehensive Urology in Los Angeles.

Frequently Asked Questions

What is the best testosterone booster?

Clomid for men is the best testosterone booster for those who are not ready to try TRT Therapy. Several studies have confirmed that clomid for men can gradually boost testosterone levels with less side effects than TRT Therapy. Each case is different which is why it’s important to consult with a board certified urologist and get your testosterone levels checked. 

What are the common side effects associated with testosterone replacement therapy?

Common side effects include acne, mood swings, and changes in libido. More serious risks might involve cardiovascular issues and prostate concerns. Consulting with a healthcare provider can help address specific side effects and monitor health regularly.

How can one find testosterone replacement therapy services nearby?

Locating TRT services can start with a consultation from a primary care physician or endocrinologist. Search online directories or medical websites to find experienced professionals offering TRT. It’s essential to choose a clinic or healthcare provider experienced in hormone treatments.

What is the process for starting testosterone replacement therapy?

Starting TRT typically involves a thorough evaluation by a healthcare provider, including blood tests to confirm low testosterone levels. Once confirmed, they develop a tailored treatment plan, which may include injections, patches, or gels. Regular follow-ups ensure the treatment’s effectiveness and safety.

What changes can be expected before and after testosterone replacement therapy?

Before starting TRT, individuals may suffer from fatigue and reduced muscle mass. Post-therapy, they often notice increased energy levels, improved mood, and enhanced muscle strength. Each patient’s experience varies, and setting realistic expectations with a healthcare provider is important.

At what age is it appropriate to consider testosterone replacement therapy?

TRT is commonly considered for individuals experiencing low testosterone symptoms, typically after middle age. Factors such as declining energy and libido may prompt consideration in younger individuals, but it’s critical to consult with a healthcare provider for a thorough evaluation to determine appropriate timing and necessity.

Kia Michel, MD

Kia Michel, MD

Written by Dr. Kia Michel, a board certified urologist, surgeon, and founding member of Comprehensive Urology in Beverly Hills, Los Angeles. Dr. Michel's expertise includes focal therapy (HIFU/TULSA), prostate cancer treatment, robotic surgery, and male enhancement treatments such as Shockwave Therapy for ED and penile injections.

Dr. Michel's Bio

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